In a bowl, combine chicken thighs and buttermilk. Ensure chicken is fully submerged. Cover and refrigerate for at least 1 hour (or up to overnight) for maximum flavor and tenderness.
In another bowl, mix the flour, paprika, garlic powder, onion powder, salt, black pepper, and cayenne pepper. Set aside.
In a deep skillet or Dutch oven, pour enough vegetable oil to cover the bottom about 1-2 inches deep. Heat the oil over medium-high heat until it reaches 350°F (175°C).
Remove the marinated chicken from the buttermilk, allowing excess to drip off. Dredge each piece in the seasoned flour mixture, pressing firmly to ensure an even coating. Shake off any excess flour.
Carefully place the coated chicken into the hot oil, cooking in batches if necessary to avoid overcrowding. Fry for about 5-7 minutes on each side or until golden brown and internal temperature reaches 165°F (75°C). Remove and place on a paper towel-lined plate to drain excess oil.
In a small bowl, combine honey and chopped jalapeños. Mix well to infuse the honey with heat.
Toast the brioche buns until golden. Spread a generous amount of the jalapeño honey on the bottom half of each bun. Place a piece of fried chicken on top, then add lettuce, tomato slices, and pickles. Finally, drizzle more jalapeño honey over the chicken before placing the top half of the bun.
Serve the sandwiches hot with extra jalapeño honey on the side for dipping if desired.
Notes
Adjust the cayenne pepper for desired spice level.